bispecific monoclonal antibody

A monoclonal antibody that binds two different types of antigen. Bispecific monoclonal antibodies do not occur naturally; they must be made in the laboratory.

English dictionary of cancer terms . 2015.

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  • Bispecific monoclonal antibody — A bispecific monoclonal antibody is a monoclonal antibody that binds two different types of antigen. Bispecific monoclonal antibodies do not occur naturally; they must be made in the laboratory. External links *… …   Wikipedia

  • Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… …   Wikipedia

  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • Bispecific antibody — A bispecific antibody is a monoclonal antibodies which is designed to bind to two different antigens.One benefit of this approach is that it is possible for such an antibody to simultaneously bind to a cytotoxic cell (using a receptor like CD3)… …   Wikipedia

  • Single-domain antibody — Ribbon diagram of a llama VHH domain. The extended CDR3 loop is coloured orange. A single domain antibody (sdAb, called Nanobody by Ablynx, the developer[1]) is an antibody fragment consisting …   Wikipedia

  • Bispezifischer Antikörper — Ein bispezifischer Antikörper (Abkürzung: BsMAb von engl. bispecific monoclonal antibody), auch als Hybrid Antikörper bezeichnet, ist ein Immunkonjugat, das aus Bestandteilen von zwei unterschiedlichen monoklonalen Antikörpern aufgebaut sind.… …   Deutsch Wikipedia

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

  • Chemically linked Fab — Example of chemically linked Fabs: two Fab fragments linked with a thioether, resulting in a F(ab )2. The molecule is bound to a tumour cell via the tumour antigen CD30 and to a macrophage via an Fc receptor. Two chemically linked fragments… …   Wikipedia

  • Single-chain variable fragment — Rotating scFv fragment with highlighted complementary determining regions (CDRs) …   Wikipedia

  • Microantibody — A microantibody is an artificial short chain of amino acids copied from a fully functional natural antibody. Microantibodies can stop viruses such as HIV infecting cells in vitro.[1] Antibodies are produced naturally by the body and play a key… …   Wikipedia

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