VB4-845

A substance being studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of epithelial cells and some types of cancer cells). Also called anti-EpCAM-Pseudomonas-exotoxin fusion protein and Proxinium.

English dictionary of cancer terms . 2015.

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  • anti-EpCAM-Pseudomonas-exotoxin fusion protein — A substance being studied in the treatment of certain types of head and neck cancer. Anti EpCAM Pseudomonas exotoxin fusion protein is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM …   English dictionary of cancer terms

  • Proxinium — A substance being studied in the treatment of certain types of head and neck cancer. Proxinium is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of… …   English dictionary of cancer terms

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