SU11248

A drug used to treat gastrointestinal stromal tumors (GIST) that have not responded to treatment with imatinib mesylate (Gleevec). SU11248 is also used to treat advanced kidney cancer and is being studied in the treatment of other types of cancer. It is a type of tyrosine kinase inhibitor, vascular endothelial growth factor (VEGF) receptor inhibitor, and angiogenesis inhibitor. Also called sunitinib, sunitinib malate, SU011248, and Sutent.

English dictionary of cancer terms . 2015.

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  • Sunitinib — drugbox IUPAC name = N [2 (diethylamino)ethyl] 5 [( Z ) (5 fluoro 1,2 dihydro 2 oxo 3 H indol 3 ylidine)methyl] 2,4 dimethyl 1 H pyrrole 3 carboxamide CAS number = 341031 54 7 ATC prefix = L01 ATC suffix = XE04 PubChem = 5329102 DrugBank = C = 22 …   Wikipedia

  • Sunitinib — Nombre (IUPAC) sistemático N [2 (diethylamino)ethyl] 5 [(Z) (5 fluoro 1,2 dihydro 2 oxo 3H indol 3 ylidine)methyl] 2,4 dimethyl 1H pyrrole …   Wikipedia Español

  • Joseph Schlessinger — Joseph Schlessinger, Ph.D. is Chair of the Pharmacology Department at Yale University School of Medicine in New Haven, Connecticut. His area of research is signaling through tyrosine phosphorylation which is important in many areas of cellular… …   Wikipedia

  • CDH11 — Cadherin 11, type 2, OB cadherin (osteoblast), also known as CDH11, is a human gene.cite web | title = Entrez Gene: CDH11 cadherin 11, type 2, OB cadherin (osteoblast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • SU011248 — A drug used to treat gastrointestinal stromal tumors (GIST) that have not responded to treatment with imatinib mesylate (Gleevec). SU011248 is also used to treat advanced kidney cancer and is being studied in the treatment of other types of… …   English dictionary of cancer terms

  • sunitinib — A drug used to treat gastrointestinal stromal tumors (GIST) that have not responded to treatment with imatinib mesylate (Gleevec). Sunitinib is also used to treat advanced kidney cancer and is being studied in the treatment of other types of… …   English dictionary of cancer terms

  • sunitinib malate — A drug used to treat gastrointestinal stromal tumors (GIST) that have not responded to treatment with imatinib mesylate (Gleevec). Sunitinib malate is also used to treat advanced kidney cancer and is being studied in the treatment of other types… …   English dictionary of cancer terms

  • Sutent — A drug used to treat gastrointestinal stromal tumors (GIST) that have not responded to treatment with imatinib mesylate (Gleevec). Sutent is also used to treat advanced kidney cancer and is being studied in the treatment of other types of cancer …   English dictionary of cancer terms

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