selective estrogen receptor modulator
- SERM. A drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues. Tamoxifen and raloxifene are SERMs. Also called SERM.
English dictionary of cancer terms . 2015.
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Selective estrogen receptor modulator — Selective Estrogen Receptor Modulators (SERMs) are a class of medication that acts on the estrogen receptor.cite journal |author=Riggs BL, Hartmann LC|title=Selective estrogen receptor modulators mechanisms of action and application to clinical… … Wikipedia
selective estrogen receptor modulator — n any of a class of drugs (as raloxifene or tamoxifen) that bind with estrogen receptors and act as estrogen agonists in some tissues and estrogen antagonists in other tissues abbr. SERM * * * (SERM) an agent that activates some estrogen… … Medical dictionary
Selective Estrogen-Receptor Modulator (SERM) — A "designer estrogen" which possesses some, but not all, of the actions of estrogen. For example, raloxifene (trade name EVISTA) is classified as a SERM because it prevents bone loss (like estrogen) and lowers serum cholesterol (like… … Medical dictionary
Selective androgen receptor modulator — Selective androgen receptor modulators or SARMs are a novel class of androgen receptor ligands. (The name follows the terminology currently used for similar molecules targeting the estrogen receptor, selective estrogen receptor modulators, such… … Wikipedia
Selective progesterone receptor modulator — A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor. A characteristic that distinguishes such substances from receptor full agonists (such as progesterone) and full antagonists (such as RU 486) is … Wikipedia
selective (o)estrogen receptor modulator — SERM a drug that has oestrogen like activity in some tissues and an anti oestrogenic effect in others, depending on the manner of its binding with the oestrogen receptors. Tamoxifen was the first SERM to be introduced. Because of its activity as… … The new mediacal dictionary
Selective glucocorticoid receptor agonist — DIGRA redirects here. For the Digital Games Research Association, see DiGRA. Mapracorat, one of the furthest developed SEGRAs A selective glucocorticoid receptor agonist (SEGRA), sometimes called a dissociated glucocorticoid receptor … Wikipedia
Estrogen receptor beta — See also: Estrogen receptor Estrogen receptor 2 (ER beta) PDB rendering based on 1hj1 … Wikipedia
Estrogen-related receptor gamma — PDB rendering based on 1kv6 … Wikipedia
modulator — That which regulates or adjusts. selective estrogen receptor m. (SERM) pharmaceutical agent with selective estrogen receptor affinity; current preparations have a primary effect on bone and … Medical dictionary