recombinant adenovirus-p53

A substance that has been studied in the treatment of some types of cancer. Recombinant adenovirus-p53 is a weakened adenovirus that carries the p53 gene into tumor cells, causing them to die. It is a type of gene therapy. Also called SCH-58500, ACN53, and rAd/p53.

English dictionary of cancer terms . 2015.

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  • rAd/p53 — A substance that has been studied in the treatment of some types of cancer. rAd/p53 is a weakened adenovirus that carries the p53 gene into tumor cells, causing them to die. It is a type of gene therapy. Also called recombinant adenovirus p53,… …   English dictionary of cancer terms

  • ACN53 — A substance that has been studied in the treatment of some types of cancer. ACN53 is a weakened adenovirus that carries the p53 gene into tumor cells, causing them to die. It is a type of gene therapy. Also called recombinant adenovirus p53,… …   English dictionary of cancer terms

  • SCH-58500 — A substance that has been studied in the treatment of some types of cancer. SCH 58500 is a weakened adenovirus that carries the p53 gene into tumor cells, causing them to die. It is a type of gene therapy. Also called recombinant adenovirus p53,… …   English dictionary of cancer terms

  • Рекомбинантный аденовирус р53 — * рэкамбінантны адэнавірус р53 * recombinant adenovirus p53 ослабленный вирус, содержащий ген р53, который он вносит в раковые клетки и вызывает их гибель. Его используют как один из вариантов генотерапии рака …   Генетика. Энциклопедический словарь

  • Oncolytic virus — An oncolytic virus is a virus that preferentially infects and lyses cancer cells; these have obvious functions for cancer therapy, both by direct destruction of the tumour cells, and, if modified, as vectors enabling genes expressing anticancer… …   Wikipedia

  • Onyx-015 — is an experimental oncolytic virus created by genetically engineering an adenovirus.[1] It has been trialed as a possible treatment for cancer. The E1B 55kDa gene has been deleted allowing the virus to selectively replicate in and lyse p53… …   Wikipedia

  • Gene therapy — using an Adenovirus vector. A new gene is inserted into an adenovirull. If the treatment is successful, the new gene will make a functional protein. Gene therapy is the insertion, alteration, or removal of genes within an individual s cells and… …   Wikipedia

  • Gendicine — ist ein Arzneimittel zur Behandlung von Krebserkrankungen auf der Basis eines gentechnologisch veränderten Adenovirus. Es wurde am 16. Oktober 2003 von der entsprechenden Behörde in der Volksrepublik China für den klinischen Einsatz bei Patienten …   Deutsch Wikipedia

  • Proliferating cell nuclear antigen — The assembled human DNA clamp, a trimer of the protein PCNA …   Wikipedia

  • Thérapie génique — à base d un vecteur adénovirus. Un nouveau gène est inséré dans un vecteur dérivé d un adénovirus, lequel est utilisé pour introduire l ADN modifié dans une cellule humaine. Si le transfert se déroule correctement, le nouveau gène élaborera une… …   Wikipédia en Français

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