athymic nude mouse

A type of laboratory mouse that is hairless, lacks a normal thymus gland, and has a defective immune system because of a genetic mutation. Athymic nude mice are often used in cancer research because they do not reject tumor cells, from mice or other species.

English dictionary of cancer terms . 2015.

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  • nude mouse — n(y)üd n a mouse of a hairless strain bred for laboratory use that lacks a thymus and mature T cells and is used esp. in immunological research * * * a mouse born without a thymus and therefore no T lymphocytes. Human tumours will often grow in… …   Medical dictionary

  • Nude mouse — A nude mouse A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype, or main outward… …   Wikipedia

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  • Secreted frizzled-related protein 1 — The Secreted frizzled related protein (SFRP) family consists of five secreted glycoproteins in humans ( 300 amino acids in length) that act as extracellular signaling ligands. Each SFRP contains a cysteine rich domain (CRD) that shares 30 50%… …   Wikipedia


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