- A drug that prevents the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy for postmenopausal women who have hormone-dependent breast cancer.
English dictionary of cancer terms . 2015.
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Aromatase inhibitor — Aromatase inhibitors (AI) are a class of drugs used in the treatment of breast cancer and ovarian cancer in postmenopausal women that block the aromatase enzyme.Type I and IIAIs are categorized into two types: [cite journal |author=Mokbel K… … Wikipedia
Aromatase inhibitor — A drug that inhibits the enzyme aromatase and thus lowers the level of the estrogen, estradiol. Aromatase inhibitors are a class of antiestrogens. Aromatase catalyzes the conversion of testosterone (an androgen) to estradiol (an estrogen) in… … Medical dictionary
aromatase inhibitor — any one of a class of drugs used in the treatment of early and advanced oestrogen dependent breast cancer in postmenopausal women. These drugs act by inhibiting the action of aromatase, an enzyme that promotes the conversion of testosterone to… … The new mediacal dictionary
nonsteroidal aromatase inhibitor — A drug that decreases the production of sex hormones (estrogen or testosterone) and slows the growth of tumors that need sex hormones to grow … English dictionary of cancer terms
Aromatase — Bändermodell nach PDB … Deutsch Wikipedia
Aromatase — Cytochrome P450, family 19, subfamily A, polypeptide 1 Crystallographic structure of the human aromatase cytochrome P450 (rainbow colored cartoon, N terminus = blue, C terminus = red) in complex with the cofactor protoporphyrin IX (top) and the… … Wikipedia
inhibitor — 1. An agent that restrains or retards physiologic, chemical, or enzymatic action. 2. A nerve, stimulation of which represses activity. SEE ALSO: inhibition. α glucosidase i. an oral agent that aids in th … Medical dictionary
Monoamine oxidase inhibitor — MAOI redirects here. For the Easter Island statues, see Moai. Monoamine oxidase Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. They are particularly effective in treating… … Wikipedia
Phosphodiesterase inhibitor — A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and… … Wikipedia
Dihydrofolate reductase inhibitor — A dihydrofolate reductase inhibitor is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate. Since folate is needed by rapidly dividing cells to make thymine, this effect may be used to therapeutic… … Wikipedia