anti-EpCAM-Pseudomonas-exotoxin fusion protein

A substance being studied in the treatment of certain types of head and neck cancer. Anti-EpCAM-Pseudomonas-exotoxin fusion protein is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of epithelial cells and some types of cancer cells). Also called VB4-845 and Proxinium.

English dictionary of cancer terms . 2015.

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  • Proxinium — A substance being studied in the treatment of certain types of head and neck cancer. Proxinium is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of… …   English dictionary of cancer terms

  • VB4-845 — A substance being studied in the treatment of certain types of head and neck cancer. VB4 845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of… …   English dictionary of cancer terms

  • Immuntoxin — Schematische Darstellung der Endozytose eines Immuntoxins in einer Krebszelle. Immuntoxine, auch als Immunotoxine bezeichnet, sind Immunkonjugate, die aus einer zellbindenden Komponente und einem Toxin bestehen. Immuntoxine sind potenzielle… …   Deutsch Wikipedia

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