fusion protein

A protein created by joining two genes together. Fusion proteins may occur naturally or can be created in the laboratory for research.

English dictionary of cancer terms . 2015.

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  • fusion protein — Protein formed by expression of a hybrid gene made by combining two gene sequences. Typically this is accomplished by cloning a cDNA into an expression vector in frame with an existing gene, perhaps encoding eg. beta galactosidase. See GST fusion …   Dictionary of molecular biology

  • Fusion protein — This article is about chimeric fusion proteins. For proteins involved in membrane fusion, see membrane fusion protein. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes which originally coded for… …   Wikipedia

  • fusion protein — A polypeptide translated from a chimeric gene. The different genes are joined so that their coding sequences are in the same reading frame, and the resulting construct is transcribed and translated as a single gene, producing a single protein.… …   Glossary of Biotechnology

  • fusion protein — noun A protein formed by genetically fusing or combining a gene encoding a target protein of interest with a gene encoding a protein or portion of protein that adds a desired functionality to target …   Wiktionary

  • fusion protein — a protein produced by a recombinant DNA construct engineered such that the coding region of one gene is linked distal to the 5′ end of another gene and within its coding region, placing expression of both genes under regulatory control of… …   Medical dictionary

  • N-ethylmaleimide sensitive fusion protein — N ethylmaleimide sensitive factor PDB rendering based on 1d2n …   Wikipedia

  • Membrane fusion protein — Membrane fusion proteins are membrane proteins which cause more than one membrane to combine. Examples include: SNARE (protein), such as VAMP Gp41 See also Fusion protein Interbilayer Forces in Membrane Fusion External links MeSH… …   Wikipedia

  • Tpr-met fusion protein — is an oncogene fusion protein consisting of TPR and MET.[1] References ^ Mak HH, Peschard P, Lin T, Naujokas MA, Zuo D, Park M (2007). Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr Met, involves exclusion from the… …   Wikipedia

  • Bcr-abl fusion protein — is an oncogene fusion protein consisting of BCR and ABL.It is associated with Philadelphia chromosome.BCR ABL Fusion Protein comes in three flavors P190, P210 and P230 depending on the breakpoint on the BCR Fragment. The P190 isoform can be… …   Wikipedia

  • 72F fusion protein — is a candidate tuberculosis vaccine created by Statens Serum Institut (SSI). The 72F fusion protein is composed of the Rv0125 and Rv1196 proteins derived from Mycobacterium tuberculosis . Phase I clinical trials were completed in 2005 and Phase… …   Wikipedia

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