endothelin receptor antagonist
- A drug that blocks the hormone endothelin and may prevent prostate cancer from spreading to the bones. It may also prevent the growth and spread of other types of cancer, including colorectal cancer.
English dictionary of cancer terms . 2015.
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Endothelin receptor antagonist — A endothelin receptor antagonist (ERA) is a drug which blocks endothelin receptors. Two main kinds of ERAs exist: * selective ERA (e.g. sitaxsentan), which affect endothelin A. * dual ERAs,(e.g. bosentan) which affect both endothelin A and B . [… … Wikipedia
Receptor antagonist — This article is about the biochemistry term. For other uses, see Antagonist (disambiguation). Antagonists will block the binding of an agonist at a receptor molecule, inhibiting the signal produced by a receptor agonist coupling. A receptor… … Wikipedia
Endothelin receptor — protein Name=endothelin receptor type A caption= width= HGNCid=3179 Symbol=EDNRA AltSymbols= EntrezGene=1909 OMIM=131243 RefSeq=NM 001957 UniProt=P25101 PDB= ECnumber= Chromosome=4 Arm=q Band=31.2 LocusSupplementaryData=protein Name=endothelin… … Wikipedia
endothelin-1 protein receptor antagonist — A substance that blocks the binding of the endothelin 1 protein to its receptor. Endothelin 1 is a small molecule that causes changes in blood vessels and helps regulate blood pressure. It can also stimulate the growth of some types of cells … English dictionary of cancer terms
NMDA receptor antagonist — Ketamine, one of the most common NMDA receptor antagonists. NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the N methyl d aspartate receptor (NMDAR). They are used as anesthesia for animals … Wikipedia
Cannabinoid receptor antagonist — The discovery of the endogenous cannabinoid system led to the development of CB1 receptor antagonists. The first cannabinoid receptor antagonist, rimonabant, was described in 1994. Rimonabant blocks the CB1 receptor selectively and it has been… … Wikipedia
NK1 receptor antagonist — Neurokinin 1 (NK1) antagonists are a novel class of medications that possesses unique antidepressant, anxiolytic, and antiemetic properties. The discovery of neurokinin 1 (NK1) receptor antagonists was a turning point in the prevention of… … Wikipedia
Endothelin — protein Name = Endothelin 2 width = caption = Symbol = EDN2 AltSymbols = ATC prefix= ATC suffix= ATC supplemental= CAS number= CAS supplemental= DrugBank= EntrezGene = 1907 HGNCid =3177 OMIM = 131241 PDB = RefSeq = NM 001956 UniProt = P20800… … Wikipedia
Nicotinic antagonist — A nicotinic antagonist is a type of anticholinergic that inhibits the action at nicotinic acetylcholine receptors. These compounds are mainly used for peripheral muscle paralysis in surgery, but some centrally acting compounds such as bupropion,… … Wikipedia
5-HT3 antagonist — 5 HT3 receptor antagonists Drug class Skeletal formula of ondansetron, the prototypical 5 HT3 antagonist ATC code A04AA … Wikipedia