matrix metalloproteinase
A member of a group of enzymes that can break down proteins, such as collagen, that are normally found in the spaces between cells in tissues (i.e., extracellular matrix proteins). Because these enzymes need zinc or calcium atoms to work properly, they are called metalloproteinases. Matrix metalloproteinases are involved in wound healing, angiogenesis, and tumor cell metastasis.

English dictionary of cancer terms . 2015.

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  • Matrix métalloprotéinase — Métalloprotéinase matricielle Les métalloprotéinases matricielles ou MMP (de l anglais Matrix metalloproteinase) sont des enzymes qui dégradent la matrice extracellulaire des tissus conjonctifs, notamment de la peau. Il en existe de nombreux… …   Wikipédia en Français

  • Matrix metalloproteinase — Cell surface associated MT1 MMP (MMP14), Green fluorescent protein (GFP) fused to the C term produces a signal on the surface of the cell[1] Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases; other family members are adamalysins …   Wikipedia

  • matrix metalloproteinase — (MMP) any of a group of endopeptidases that hydrolyze proteins of the extracellular matrix; faulty regulation of MMP activity resulting in excessive matrix degradation contributes to degenerative diseases such as arthritis and to tumor metastasis …   Medical dictionary

  • matrix metalloproteinase — MMP any one of a group of zinc containing proteases capable of digesting the extracellular tissue matrix. These enzymes play an important role in cell division, cell migration, inflammation, neoplastic invasion (metastasis), and angiogenesis …   The new mediacal dictionary

  • Matrix metalloproteinase inhibitor — A matrix metalloproteinase inhibitor (MMPI) inhibits matrix metalloproteinases. As they inhibit cell migration they have antiangiogenic effects. They may be both endogenous and exogenous. The most notorious endogenous metalloproteinases are… …   Wikipedia

  • Matrix metallopeptidase 13 — (collagenase 3) PDB rendering based on 1cxv …   Wikipedia

  • Metalloproteinase matricielle — Métalloprotéinase matricielle Les métalloprotéinases matricielles ou MMP (de l anglais Matrix metalloproteinase) sont des enzymes qui dégradent la matrice extracellulaire des tissus conjonctifs, notamment de la peau. Il en existe de nombreux… …   Wikipédia en Français

  • Métalloprotéinase Matricielle — Les métalloprotéinases matricielles ou MMP (de l anglais Matrix metalloproteinase) sont des enzymes qui dégradent la matrice extracellulaire des tissus conjonctifs, notamment de la peau. Il en existe de nombreux types (une trentaine… …   Wikipédia en Français

  • Matrix-Metalloproteasen — (MMP) sind eine Gruppe verwandter Enzyme, die die Spaltung von Peptidbindungen in Proteinen katalysieren (so genannte Peptidasen). Sie kommen in allen Lebewesen außer Protozoen vor. In Eukaryoten sind sie außerhalb von Zellen in der… …   Deutsch Wikipedia

  • Matrix metallopeptidase 12 — macrophage elastase Identifiers EC number 3.4.24.65 CAS number 146888 86 0 …   Wikipedia

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